I've been supporting Kiva for a couple years now. Not only are they an amazing organization with a dedicated and life-changing mission, but the way you lend (donate) is easy, intuitive and clever.
Kiva's mission is to connect people through lending for the sake of alleviating poverty. They are the world's first person-to-person micro-lending website, empowering individuals to lend to unique entrepreneurs around the globe. The people you see on the site are real individuals. When you browse entrepreneurs' profiles, you (or your gift recipient) can choose someone to lend to, and then make a loan, you are helping a real person make great strides towards economic independence and improve life for themselves, their family, and their community. Throughout the course of the loan you can receive email journal updates and track repayments. Then, when you get your loan money back, you can relend to someone else.
Kiva now offers Gift Certificates in various pre-set ammounts, perfect for that special client, friend or family member!